Biological Safety Principles and Practices

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Diane O. Fleming, Debra L. Hunt ASM Press 2006
I Hazard Identification 1 Microbial Flora of Humans and Microbial Virulence Factors / 3 PAUL A. GRANATO 2 Indigenous and Pathogenic Agents of Research Animals / 19 DIANE O. FLEMING 3 Laboratory, Growth Chamber, and Greenhouse Microbial Safety: Plant Pathogens and Plant-Associated Microorganisms of Significance to Human Health / 35 ANNE K. VIDAVER, SUE A. TOLIN, AND PATRICIA LAMBRECHT 4 Epidemiology of Laboratory-Associated Infections / 53 A.

I Hazard Identification 1 Microbial Flora of Humans and Microbial Virulence Factors / 3 PAUL A. GRANATO 2 Indigenous and Pathogenic Agents of Research Animals / 19 DIANE O. FLEMING 3 Laboratory, Growth Chamber, and Greenhouse Microbial Safety: Plant Pathogens and Plant-Associated Microorganisms of Significance to Human Health / 35 ANNE K. VIDAVER, SUE A. TOLIN, AND PATRICIA LAMBRECHT 4 Epidemiology of Laboratory-Associated Infections / 53 A. LYNN HARDING AND KAREN BRANDT BYERS II Hazard Assessment 5 Risk Assessment of Biological Hazards / 81 DIANE O. FLEMING 6 Bacterial Pathogens / 93 JOSEPH H. COGGIN, JR.7 Protozoa and Helminths / 115 BARBARA L. HERWALDT 8 Mycotic Agents of Human Disease / 163 WILEY A. SCHELL 9 Viral Agents of Human Disease: Biosafety Concerns / 179 JASON PARAGAS AND TIMOTHY P. ENDY 10 Biosafety for Microorganisms Transmitted Primarily by the Airborne Route / 209 MICHAEL A. PENTELLA, PAMELA A. KOSTLE, LUCY DESJARDIN, AND MARY J. R. GILCHRIST 11 Cell Lines: Applications and Biosafety / 221 OTTO DOBLHOFF-DIER AND GLYN STACEY 12 Allergens of Animal and Biological Systems / 241 WANDA PHIPATANAKUL AND ROBERT A. WOOD 13 Biological Toxins: Safety and Science / 253 JOSEPH P. KOZLOVAC AND ROBERT J. HAWLEY III Hazard Control 14 Design of Biomedical Laboratory Facilities / 273 JONATHAN T. CRANE AND JONATHAN Y. RICHMOND 15 Primary Barriers and Equipment-Associated Hazards / 295 ELIZABETH A. GILMAN DUANE AND RICHARD C. FINK 16 Primary Barriers: Biological Safety Cabinets, Fume Hoods, and Glove Boxes / 303 DAVID G. STUART, DAVID C. EAGLESON, AND CHARLES W. QUINT, JR. 17 Personal Respiratory Protection / 325 NICOLE VARS MCCULLOUGH 18 Standard (Universal) Precautions for Handling Human Specimens / 341 DEBRA L. HUNT 19 Prudent Biosafety Practices / 361 DIANE O. FLEMING 20 Decontamination and Disinfection / 373 MARTIN S. FAVERO AND MATTHEW J. ARDUINO 21 Packing and Shipping Biological Materials / 383 LARRY D. GRAY AND JAMES W. SNYDER vi CONTENTSIV Administrative Controls 22 Biological Safety Program Management / 405 LOUANN CRAWFORD BURNETT 23 Biosafety Compliance: a Global Perspective / 417 RICHARD REBAR AND HALLEY MORIYAMA 24 Occupational Medicine in a Biomedical Research Setting / 437 DEBORAH E. WILSON AND JAMES M. SCHMITT 25 Measuring Biosafety Program Effectiveness / 445 JANET S. PETERSON AND ROBERT J. HASHIMOTO V Special Considerations for Biosafety 26 Biosafety of Prion Diseases / 461 HENRY BARON AND STANLEY B. PRUSINER 27 Safety Considerations in the BSL-4 MaximumContainment Laboratory / 487 DAVID S. BRESSLER AND ROBERT J. HAWLEY 28 Biosafety and Viral Gene Transfer Vectors / 509 THOMAS A. KOST, PATRICK J. CONDREAY, AND CLAUDIA A. MICKELSON 29 Biosafety in the Teaching Laboratory / 531 DAVID M. CARLBERG AND MICHAEL R. YEAMAN 30 Biosafety in the Pharmaceutical Industry / 551 PAUL J. MEECHAN, JOSEPH GYURIS, BRIAN R. PETUCH, MICHEL M. CHARTRAIN, AND WAYNE K. HERBER 31 Large-Scale Production of Microorganisms / 561 MARY L. CIPRIANO 32 Special Considerations for Agriculture Pathogen Biosafety / 579 ROBERT A. HECKERT AND JOSEPH P. KOZLOVAC 33 Biosafety and Biosecurity: Regulatory Impact / 587 ROBERT J. HAWLEY AND THERESA D. DULEY

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